4-Bromophenylboronic Acid CAS 5467-74-3: Properties, Applications, and Sourcing Guide

4-Bromophenylboronic acid, also called 4-bromobenzeneboronic acid, is an arylboronic acid used as a building block in organic synthesis. Its combination of a boronic acid group and a para-positioned bromine substituent makes it useful in cross-coupling and other research or development workflows. The compound has CAS number 5467-74-3, molecular formula C₆H₆BBrO₂, and a molecular weight of 200.83 g/mol. In this guide, we explain its properties, common applications, selection considerations, and how to assess a supplier before requesting a quotation.

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Key Takeaways

• 4-Bromophenylboronic acid is a bifunctional aromatic building block containing both a boronic acid group and an aryl bromide.
• Its molecular formula is C₆H₆BBrO₂, and its molecular weight is 200.83 g/mol.
• It is commonly considered for Suzuki–Miyaura coupling and related synthetic route development, subject to reaction-specific validation.
• Before purchase, confirm the required assay, analytical documentation, packaging, quantity, and delivery destination with the supplier.

Who This Guide Is For

This guide is intended for procurement teams, research chemists, process development groups, and manufacturers evaluating 4-Bromophenylboronic acid as a synthesis intermediate. It is also relevant to buyers comparing suppliers or preparing an inquiry for a defined project quantity. The information provides a sourcing and product-selection overview, not a substitute for a validated process, safety assessment, or batch-specific documentation. We recommend checking the current specification and handling guidance for the exact material offered.

Basic Concept and Chemical Context

Structure and identity

The molecule contains a phenyl ring bearing a boronic acid group, B(OH)₂, and a bromine atom in the para, or 4-position. This arrangement allows the boronic acid functionality to participate in selected carbon–carbon bond-forming reactions while retaining an aryl bromide that may be useful for further transformations. Whether both functional groups can be used selectively depends on the substrate, catalyst, reaction conditions, and route design. Chemists should confirm chemoselectivity experimentally rather than assume that a particular sequence will work.

Useful reference data

The elemental percentages above are theoretical calculations, not batch assay results. They do not replace a certificate of analysis or other lot-specific test data. Physical appearance, purity, water content, and analytical profile should be confirmed against the offered grade and its documentation.

Applications and Application Matching

Cross-coupling and intermediate synthesis

A primary use for arylboronic acids is Suzuki–Miyaura coupling, a palladium-catalyzed method for forming carbon–carbon bonds between an organoboron reagent and an appropriate coupling partner. In route design, 4-Bromophenylboronic acid may be selected when a para-substituted aromatic unit is needed and the bromine substituent is intended to remain available for a later step. The practical outcome depends on reaction conditions and compatibility with the other functional groups in the molecule. Buyers should align the grade and quantity with the intended stage of development, from exploratory screening to process evaluation.

Medicinal chemistry and materials research

Research teams may evaluate this compound when preparing substituted biaryl structures or exploring intermediates for more complex organic molecules. It may also be considered in discovery chemistry and materials-related synthesis where an aryl bromide or boronic acid-derived bond-forming step fits the target structure. These are potential use areas rather than guarantees of performance in a given reaction. A small-scale feasibility study can help establish conversion, selectivity, and purification requirements before larger quantities are purchased.

Selection Framework for Buyers

Define the specification before comparing offers

Start by identifying the required assay or purity threshold and the analytical method expected for acceptance. Then determine whether your work requires additional controls, such as limits for water, residual solvents, or trace impurities. Not every supplier or grade will provide the same specification or testing package, so request the available documents rather than infer them from a product name. If your internal procedures require a particular test method, state it clearly in the inquiry.

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Match quantity, packaging, and timing to project needs

Estimate the quantity needed for initial trials, repeat experiments, and planned scale-up, while accounting for handling losses and any retesting requirements. Confirm the proposed package size, container type, storage recommendations, and whether the offered quantity can be divided into suitable units. Price, minimum order quantity, and lead time can vary with requested grade, quantity, production or stock status, and destination. We recommend requesting a current quotation with the shipping location and required delivery window specified.

Evaluate documentation and supply communication

Ask whether the supplier can provide a batch-specific certificate of analysis and safety data sheet for the material being quoted. Check that the product name, CAS number, batch identification, specification, and test results are consistent across the documents provided. For regulated or quality-sensitive projects, communicate your documentation and change-notification expectations before placing an order. A clear response to technical and logistics questions is an important part of evaluating supply suitability.

Pricing, MOQ, and Lead Time

There is no single price or delivery schedule that applies to every order of 4-Bromophenylboronic acid. Quotes can be influenced by order size, specification, packaging, availability, destination, and any requested documentation or special handling. Minimum order quantity may also differ by supplier and commercial arrangement. To obtain a useful comparison, send the same target quantity, grade requirements, destination, and requested delivery timing to each prospective supplier.

Common Sourcing Considerations

Check identity, grade, and intended use

CAS number matching is a useful first check, but it is not sufficient on its own to confirm that a material meets a project’s acceptance criteria. Compare the stated identity and specification with your intended reaction and quality requirements, and review the lot documentation when available. Avoid assuming that different purity grades or analytical packages are interchangeable. If your route is sensitive to impurities, discuss the relevant limits with the supplier before procurement.

Plan for safe handling and storage

Use the current safety data sheet and site procedures to determine appropriate personal protective equipment, storage conditions, and waste handling. Keep the material in its supplied container unless your laboratory or facility has an approved repackaging procedure. For transport or import, verify that the supplier and receiving organization have confirmed applicable documentation and shipping requirements. We advise buyers not to rely on generic handling assumptions when batch-specific or jurisdiction-specific instructions are available.

Working with Maison Chemical

At Maison Chemical, we support B2B buyers sourcing 4-Bromophenylboronic acid CAS 5467-74-3 for research, development, and manufacturing requirements. We can discuss your target grade, quantity, packaging expectations, destination, and documentation needs so that the proposed supply can be assessed against your application. Availability, specification, minimum order quantity, and lead time should be confirmed for each inquiry rather than assumed in advance. Where applicable, buyers can request current product and batch documentation during the quotation process.

Conclusion and Next Steps

4-Bromophenylboronic acid CAS 5467-74-3 is an aromatic boronic acid building block with a para-bromine substituent, a molecular formula of C₆H₆BBrO₂, and a molecular weight of 200.83 g/mol. Its two reactive functional groups can make it useful in selected synthetic routes, but suitability must be established for the specific reaction and project. The most reliable sourcing decision begins with a defined specification, an application-matched quantity, and a review of available batch documentation. Contact Maison Chemical with your target grade, required amount, destination, and delivery schedule to request current availability and a quotation.